Shingles (Herpes Zoster) in the Genital Region

Definition and Classification

Genital shingles is considered an anogenital herpesviral infection according to the International Classification of Diseases (ICD) 1

The vesicles contain clear fluid with high concentrations of viral particles 2
The vesicles eventually burst, forming shallow ulcers or erosions that crust and heal without scarring 2

The clinical differentiation of genital lesions can be difficult, and laboratory confirmation should be sought 3
Vesicular and/or ulcerative lesions on the genitals, buttocks, or thighs are indications for testing 4
Collection of vesicular fluid for viral testing is recommended for definitive diagnosis 3
Other conditions that may mimic genital shingles include genital herpes simplex virus (HSV) infection, which can present similarly but is caused by a different herpesvirus 3

The condition may be misdiagnosed as genital herpes (HSV infection), leading to inappropriate treatment and psychological distress 3