Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/26/2025

HIV Testing Follow-Up After Occupational Exposure: Current Guidelines

Follow-Up Testing Schedule

  • The Centers for Disease Control and Prevention recommends a testing schedule that typically includes baseline, 6 weeks, 3 months, and 6 months when using traditional antibody-only tests 1, 2, 3, 4, 5, 6, 7, 8, 9

Extended Follow-Up Considerations

  • The Centers for Disease Control and Prevention recommends 12-month extended follow-up for healthcare workers who become infected with HCV following exposure to a source coinfected with HIV and HCV 10

Clinical Algorithm for Follow-Up Duration

  • The Centers for Disease Control and Prevention recommends testing immediately if acute retroviral syndrome symptoms develop, regardless of timeline 1, 2, 10

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