Adderall XR Dosing and Monitoring Guidelines

Introduction to Adderall XR

The American Academy of Child and Adolescent Psychiatry recommends starting Adderall XR at 10 mg once daily in the morning, titrating by 5 mg weekly increments based on response and tolerability, up to a maximum of 50 mg daily 1, 2, 3, 4

The American Academy of Child and Adolescent Psychiatry suggests beginning with 10 mg orally once daily in the morning for all patients regardless of age (adults, adolescents, and children over 6 years) 1, 2, 3, 4, 5
Administer Adderall XR in the early morning to minimize sleep disturbances, as recommended by the Journal of the American Academy of Child and Adolescent Psychiatry 6, 7

Increase Adderall XR by 5 mg weekly increments if symptoms are not adequately controlled and the medication is well-tolerated, according to the American Academy of Child and Adolescent Psychiatry 1, 2, 3, 4, 5
Allow at least one week between dose increases to properly evaluate therapeutic response and side effects, as suggested by the American Academy of Child and Adolescent Psychiatry 5, 8

The American Academy of Child and Adolescent Psychiatry recommends a maximum daily dose of 50 mg for adults 1, 2, 3, 4, 5
The maximum daily dose for children is 40 mg for those weighing over 25 kg, according to the Journal of the American Academy of Child and Adolescent Psychiatry 6, 7

Obtain ADHD rating scales from teachers and parents (for children) or from the patient and significant other (for adults) before each dose increase, as recommended by the Journal of the American Academy of Child and Adolescent Psychiatry 6, 7, 5
Assess vital signs (blood pressure and pulse) at baseline and with each dose adjustment, as suggested by the Journal of the American Academy of Child and Adolescent Psychiatry 6, 7, 5, 8
Monitor weight regularly, as decreased appetite and weight loss are common side effects, according to the Journal of the American Academy of Child and Adolescent Psychiatry 6, 7, 5, 8

The American College of Obstetricians and Gynecologists recommends a usual starting dose of 10 mg once daily in the morning, titrated by 5 mg weekly up to 50 mg maximum for pregnant women 1, 2, 3, 4
Amphetamines do not appear to be associated with major congenital malformations, though there may be small increased risks for gastroschisis, preeclampsia, and preterm birth, according to the American College of Obstetricians and Gynecologists 1, 2, 3, 4
Monitor breastfed infants carefully for irritability, insomnia, and feeding difficulty, as recommended by the American College of Obstetricians and Gynecologists 1, 2, 3, 4