Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/2/2025

Laser Treatment for Skin Conditions

Pre-Treatment Preparation

  • Clean and properly humidify the treatment area and equipment to ensure a safe treatment environment 1
  • Maintain oxygen concentration below 40% to minimize fire risk 2, 3

Treatment Settings

  • For optimal CO2 laser settings, use low power settings of 1-3 W with 0.1-second pulses in intermittent mode, and utilize a small-spot (0.3 mm) micromanipulator to minimize thermal damage while ensuring effective tissue ablation 2
  • Initial coagulation settings should be 30-45 watts with 1-second pulse duration at 1 cm distance for initial coagulation before resection 2
  • For optimal CO2 laser Multi-Line Scan treatments, use low pulse repetition rates (10-60 Hz) with focused beam delivery achieving power density >60 kW/mm² to minimize thermal damage while maintaining effective tissue ablation 4

Safety Precautions

  • Continuous suction to remove smoke is mandatory, and a carbon dioxide fire extinguisher must be immediately available in the operating room 2, 3
  • Avoid wrapping tubes in metal foil, as it is a historical practice that should be avoided, and remember that no laser-tracheal tube is completely laser-proof; all are only laser-resistant 3
  • If an airway fire occurs, stop the laser immediately, call for help, activate the fire alarm, and retrieve a carbon dioxide fire extinguisher, then follow a step-by-step protocol to extinguish the fire and ensure patient safety 3

Treatment Outcomes

  • The American Academy of Dermatology recommends CO2 laser treatments for hidradenitis suppurativa, with positive outcomes in multiple uncontrolled retrospective series for Hurley stage II or III disease 4
  • Scanner-assisted CO2 laser treatment under topical anesthesia has shown low recurrence rates (1.1%) and high patient satisfaction (95% reporting improvement and 91% recommending the procedure) 5
  • Recurrence rates within treated areas range from 1.1% to 29% depending on technique, and new lesions may develop adjacent to treated areas (35.3% of cases) despite successful treatment of the target site 5
  • Flares in untreated areas occur in 73.5% of hidradenitis suppurativa patients, and caution is advised for lower leg lesions due to the risk of progression to invasive carcinoma (12% within 12 months) if treatment depth is inadequate 5, 6

Post-Treatment Care

  • Delayed epithelial healing may occur with certain underlying conditions, according to the Ophthalmology journal 7