Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/3/2025

Management of Mydriasis in Patients Receiving Antidepressants

Patient Monitoring and Care

  • For patients with both mydriasis and angle-closure concerns, careful monitoring of intraocular pressure and pupil size is recommended when starting any antidepressant 1
  • Patients with a history of narrow angles or glaucoma require particular caution when prescribing any psychotropic medication 1
  • Monitor for signs of angle-closure glaucoma, including eye pain, blurred vision, and halos around lights 1