Efficacy of Lactic‑Acid–Based Chemical Peels for Periorbital Aging

Clinical Outcomes

• In a controlled evaluation of a combined peel (trichloroacetic acid 3.75 % + lactic acid 15 %), 38 % of treated individuals achieved excellent improvement, while 93–97 % experienced fair‑to‑excellent improvement in periorbital wrinkles and skin laxity【1】.

• The same formulation is described as the gold‑standard chemical peel for periorbital rejuvenation, reflecting its preferred status among professional skin‑rejuvenation procedures【1】.

Patient Counseling Recommendations

• Patients should be advised to maintain adequate sun protection to prevent collagen degradation and preserve the benefits of the peel【2】.

• Clinicians must emphasize that visible results typically require several months of consistent treatment, rather than a few weeks, to allow for collagen remodeling【1】.