Medroxyprogesterone Acetate Duration for Withdrawal Bleeding in PCOS

Standard Dosing Protocol

• The American College of Obstetricians and Gynecologists recommends medroxyprogesterone acetate (MPA) for 10-14 days, with the standard regimen being 10 mg daily for 10 days, for inducing withdrawal bleeding in PCOS patients 1, 2

Clinical Considerations Specific to PCOS

• The Endocrine Society suggests that MPA 10 mg daily for 14 days can be used as part of ongoing cyclic therapy for withdrawal bleeding induction in PCOS patients 1, 2