Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/2/2025

Hyperthyroidism Diagnosis and Treatment

Common Symptoms

  • The American Academy of Family Physicians notes that hyperthyroidism is characterized by tremors, nervousness, insomnia, excessive sweating, heat intolerance, tachycardia, hypertension, and goiter 1
  • Hair loss is a symptom of hyperthyroidism, as reported by the Annals of Internal Medicine 2
  • Insomnia is a common symptom of hyperthyroidism, according to the American family physician and the Annals of Internal Medicine 1, 2
  • Hyperactivity is a symptom of hyperthyroidism, as noted by the Annals of Internal Medicine 2

Cardiovascular Manifestations

  • The American Heart Association, as reported in Circulation, states that hyperthyroidism is associated with decreased systemic vascular resistance, increased cardiac output, and potential pulmonary artery hypertension 3
  • Potential heart failure in severe cases of hyperthyroidism is a concern, as noted by the American family physician and Circulation 1, 3

Treatment Options

  • The American Society of Clinical Oncology recommends beta-blockers, such as atenolol or propranolol, to control heart rate and reduce tremors in patients with hyperthyroidism 4, 5
  • Hydration and supportive care are essential for symptomatic relief in patients with hyperthyroidism, as reported by the Journal of Clinical Oncology 5
  • Pregnancy requires careful monitoring, as hyperthyroidism increases the risk of severe preeclampsia, preterm delivery, and heart failure, according to the American family physician 1

Complications of Untreated Hyperthyroidism

  • Cardiovascular complications, including atrial fibrillation and heart failure, are associated with untreated hyperthyroidism, as noted by Circulation 3
  • Adverse pregnancy outcomes are a concern in untreated hyperthyroidism, as reported by the American family physician 1
  • Thyroid storm, a rare but life-threatening emergency, can occur in untreated hyperthyroidism, according to the American family physician 1