Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 7/6/2025

Ethylene Glycol Poisoning Treatment

Introduction to Ethylene Glycol Poisoning

  • The toxic effects of ethylene glycol come primarily from its metabolites (glycolic acid and oxalic acid), not the parent compound 1

Diagnosis and Laboratory Tests

  • No specific facts to report in this section with a citation id.

Treatment with Antidotes

  • No specific facts to report in this section with a citation id.

Indications for Hemodialysis

  • Intermittent hemodialysis is preferred over continuous kidney replacement therapy when available 1

Treatment Duration and Monitoring

  • Cessation of ECTR is recommended once the anion gap is <18 mmol/L or ethylene glycol concentration is <4 mmol/L 1

Additional Treatment Considerations

  • Activated charcoal is ineffective for ethylene glycol poisoning 2