Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 1/2/2026

Management of Hyperthermia in Infants

Initial Assessment and Temperature Management

  • The American Heart Association recommends removing excessive clothing or blankets to help reduce temperature in infants with hyperthermia, and ensuring the baby is in a room with appropriate temperature (23-25°C) 1, 2, 3
  • Hyperthermia (>38.0°C) should be avoided due to potential associated risks including increased mortality, seizures, and adverse neurologic outcomes, as stated by the American College of Cardiology 3, 4
  • The American College of Cardiology advises against using thermal mattresses in full-term infants as they increase risk of hyperthermia 1, 2
  • Monitoring for signs of serious illness, including poor feeding, decreased activity, and difficulty breathing, is crucial in infants with hyperthermia 3, 5

Immediate Actions

  • The American Heart Association suggests ensuring the baby's environment is at a comfortable temperature (23-25°C) to prevent overheating 1, 3
  • Avoiding methods that could cause hyperthermia (>38.0°C) is recommended, as it carries potential associated risks, according to the American College of Cardiology 3, 5

Evidence‑Based Recommendations for Neonatal Hyperthermia Management

Immediate Temperature‑Control Measures

Clinical Risks Associated with Neonatal Hyperthermia

Maternal Fever During Labor and Neonatal Outcomes