Mechanism of Action of Saroglitazar

Secondary Mechanisms and Tissue-Specific Effects

• Saroglitazar modulates adhesion molecule expression and cytokine production, providing anti-inflammatory effects through PPAR-α/γ-mediated mechanisms, as reported by the Redox Biology journal 1
• Saroglitazar interferes with the transactivation capacity of signal transducers and activators of transcription (STATs), contributing to its anti-inflammatory properties, according to the Redox Biology journal 1
• Saroglitazar reduces oxidative damage through PPARγ-mediated mechanisms, as part of its antioxidant effects, as noted in the Redox Biology journal 1