Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/14/2025

Causes and Considerations for Failed OAE Testing

Primary Causes: Outer and Middle Ear Dysfunction

  • Debris in the ear canal is the leading cause of OAE failure, accounting for the majority of false-positive results 1, 2, 3, 4, 5
  • OAEs are particularly sensitive to middle ear effusions because the acoustic signal must travel through the middle ear space in both directions 6
  • Both OAE and ABR technologies are affected by middle ear dysfunction, as these transient conditions prevent sound transmission to the cochlea 1, 2, 3, 4, 5

Secondary Causes and Risk Factors

  • Motion artifacts interfere with test results, requiring the infant to be relatively inactive during testing 6
  • The acoustic and electrical environment must be suitable for testing 1, 2, 4, 5
  • Repeated screening increases the likelihood of obtaining a pass outcome by chance alone when statistical probability is used for pass/fail decisions 1, 2, 3, 4, 5

True Hearing Loss (Less Common in Initial Failures)

  • OAE testing will miss mild or isolated frequency region losses 1, 2, 3, 4, 5
  • OAE cannot detect auditory neuropathy/dyssynchrony because OAEs are generated within the cochlea and do not assess neural function 1, 2, 3, 4, 5
  • Neural conduction disorders affecting the eighth nerve or auditory brainstem pathway will not be detected by OAE testing 1, 2, 3, 4, 5

Critical Clinical Pitfalls

  • Many well-infant screening protocols incorporate outpatient rescreening within 1 month of discharge to minimize unnecessary referrals 1, 2, 3
  • NICU infants require ABR screening rather than OAE alone, as they are at higher risk for auditory neuropathy 3