Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/12/2025

Insight in Manic Hallucinations

Diagnostic Considerations

  • The American Academy of Ophthalmology notes that Charles Bonnet Syndrome (CBS) hallucinations, which occur in visually impaired patients, are characterized by good insight where patients recognize that what they see is not real 1
  • Atypical features that suggest diagnoses other than CBS include lack of insight into the unreal nature of the images, images that interact with the patient, or other associated neurological signs, according to the American Academy of Ophthalmology 1
  • The American Psychiatric Association includes three insight specifiers for obsessive-compulsive and related disorders: good/fair insight, poor insight, and absent insight/delusional beliefs, as stated in the Nature Reviews Disease Primers 4

Clinical Implications

  • The American College of Radiology recommends that when evaluating hallucinations, it's crucial to distinguish between primary psychiatric causes (like mania) and secondary causes such as neurological disorders 3
  • Misdiagnosing manic patients with absent insight as having a primary psychotic disorder can lead to inappropriate treatment, as noted by the Nature Reviews Disease Primers 4