Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/29/2025

Insulin Aspart Clinical Effectiveness and Safety

Pharmacokinetic and Pharmacodynamic Properties

  • Clinically significant hypoglycemia can occur with insulin therapy, though newer insulin formulations may have lower rates of severe hypoglycemia 1

Practical Considerations for Hospitalized Patients

  • For hospitalized patients, insulin aspart can be used as part of a basal-bolus regimen, which has been shown to provide better glycemic control compared to sliding scale insulin alone 2

Monitoring and Target Glucose Range

  • For hospitalized patients, a target glucose range of 140-180 mg/dL is generally recommended 3

REFERENCES

1

management of diabetes and hyperglycaemia in the hospital. [LINK]

The Lancet Diabetes and Endocrinology, 2021

2

management of diabetes and hyperglycaemia in the hospital. [LINK]

The Lancet Diabetes and Endocrinology, 2021

3

Lantus Dose Adjustment for Overnight Blood Glucose of 140 mg/dL [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025