Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/5/2025

Urethrography Procedure Guidelines

Patient Preparation and Technique

  • The patient should be placed in a position to optimize urethra visualization, and a digital rectal exam should be performed in cases of pelvic trauma to detect prostate elevation, rectal bleeding, or anal-rectal lesions, as recommended by medical guidelines 1
  • Never attempt urethral catheterization if there is blood in the urethral meatus without first performing retrograde urethrography, according to the World Journal of Emergency Surgery 2, 3, 4

Urethrography Technique

  • The urethrography procedure involves instilling contrast medium into the urethra under fluoroscopy, using either a balloon catheter or non-instrumentation techniques, with the latter being better tolerated by patients, as stated by the World Journal of Emergency Surgery 2, 3
  • The contrast medium should be administered under continuous fluoroscopic vision to visualize the entire urethra, as recommended by the World Journal of Emergency Surgery 2, 3
  • Extravasation of contrast indicates urethral injury: if the contrast fills the bladder, it suggests an incomplete lesion; if it does not fill the bladder, it suggests a complete lesion, according to the World Journal of Emergency Surgery 2, 3

Combination with Other Diagnostic Techniques

  • For preoperative evaluation of pelvic fracture injuries, retrograde urethrography should be combined with voiding cystourethrography (VCUG) and/or retrograde cystoscopy, as recommended by The Journal of Urology 5, 6
  • VCUG allows evaluation of the posterior urethra, bladder neck, and complex distraction defects, according to The Journal of Urology 5, 6

Safety Considerations

  • In cases of hemodynamic instability, all urethral investigations should be postponed, and a suprapubic catheter should be placed, as recommended by the World Journal of Emergency Surgery 2, 3
  • Avoid repeated attempts at catheterization, as they increase patient morbidity and can delay anastomotic reconstruction, according to The Journal of Urology 5, 6

Urethrography Interpretation

Diagnostic Criteria

  • The WSES-AAST guidelines establish that a urethral injury is considered incomplete when contrast extravasation is accompanied by bladder filling, indicating some degree of urethral lumen continuity, in patients with urethral trauma 7, 8, 9
  • A complete urethral lesion is characterized by contrast extravasation without bladder filling, indicating total disruption of the urethra, in patients with urethral trauma 7, 8, 9

Clinical Implications

  • Incomplete urethral lesions generally have a better prognosis than complete lesions, according to the WSES-AAST guidelines, in patients with urethral trauma 7
  • The management of urethral injuries may differ based on the severity of the lesion, as stated by the WSES-AAST guidelines, in patients with urethral trauma 7, 8
  • The presence of partial continuity can influence treatment options for urethral injuries, according to the WSES-AAST guidelines, in patients with urethral trauma 7

Limitations and Precautions

  • Distinguishing between complete and incomplete urethral lesions using retrograde urethrography can be challenging and not always accurate, as noted by the WSES-AAST guidelines, in patients with urethral trauma 7, 8
  • In uncertain cases, flexible urethroscopy may provide additional information to aid in diagnosis, according to the WSES-AAST guidelines, in patients with urethral trauma 7, 8, 9

Patient Management

  • In hemodynamically unstable patients, all urethral investigations should be postponed and a suprapubic catheter should be placed, as recommended by the WSES-AAST guidelines, in patients with urethral trauma 7, 8

REFERENCES

1

Digital Rectal Examination Before Urinary Catheterization [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

2

kidney and uro-trauma: wses-aast guidelines. [LINK]

World Journal of Emergency Surgery, 2019

3

kidney and uro-trauma: wses-aast guidelines. [LINK]

World Journal of Emergency Surgery, 2019

4

Management of Foley Catheters in Patients with Pelvic Fractures [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

7

kidney and uro-trauma: wses-aast guidelines. [LINK]

World Journal of Emergency Surgery, 2019

8

kidney and uro-trauma: wses-aast guidelines. [LINK]

World Journal of Emergency Surgery, 2019

9

kidney and uro-trauma: wses-aast guidelines. [LINK]

World Journal of Emergency Surgery, 2019