Treatment of Intertrigo in Pregnant Women

General Principles of Treatment

The American College of Obstetricians and Gynecologists recommends regular application of emollients, especially after bathing, as the basis of therapy for skin inflammatory diseases during pregnancy 2
The Infectious Diseases Society of America suggests that pregnant women with intertrigo should use local antifungal agents, such as nystatin, in combination with regular application of emollients and maintenance of dryness of affected skin areas 1, 2

The Centers for Disease Control and Prevention recommends local application of nystatin or azole antifungal agents for candidal intertrigo 1
The American Academy of Dermatology suggests using nystatin suspension 100,000 units/ml or pastilles 200,000 units for the treatment of candidal intertrigo 1
When choosing antifungal agents, it is essential to consider that some azole preparations have teratogenic potential and should be used with caution, especially in the first trimester 3, 4

In the first trimester of pregnancy, systemic azole preparations should be avoided due to their potential teratogenic effect 3, 4
After the first trimester, local azole preparations can be used cautiously if necessary 5

The American College of Obstetricians and Gynecologists recommends avoiding prolonged use of topical corticosteroids, especially high-potency ones 2
It is essential to identify and correct predisposing factors, such as diabetes or excess weight, although the specific citation for this is not provided, the general principle is supported by 2

Wearing loose, breathable clothing made from natural fabrics can help prevent relapses of intertrigo 2