Effects of Creatine and Protein Supplements on Seminal Fluid and Ejaculate

Seminal Fluid Composition and Supplements

Current medical guidelines do not identify creatine or protein supplements as factors that alter seminal fluid composition, according to the American Urological Association 1, 2
Seminal plasma hypersensitivity is a documented condition but is unrelated to dietary supplements and is not associated with infertility, as stated by the American Academy of Allergy, Asthma, and Immunology 3, 4
Dietary supplements such as creatine and protein are not mentioned in fertility guidelines as having significant impacts on semen parameters, as reported by the European Society of Human Reproduction and Embryology 5, 6

The American Urological Association (AUA) and American Society for Reproductive Medicine (ASRM) state that the benefits of supplements are of questionable clinical utility in treating male infertility 6
The American Society for Reproductive Medicine (ASRM) indicates there is insufficient evidence to recommend protein or other dietary supplements for improving male fertility 7, 6
Current evidence does not support that protein supplements have any direct effect on semen parameters or ejaculate composition, according to the European Society of Human Reproduction and Embryology 2, 5

The American Society for Reproductive Medicine (ASRM) recommends that men concerned about fertility focus on established factors that affect semen quality such as smoking, excessive alcohol, certain medications, and environmental exposures 2
Current fertility guidelines do not recommend routine use of dietary supplements including creatine or protein for improving male fertility, as stated by the American Urological Association 6
The European Society of Human Reproduction and Embryology advises men with fertility concerns to consult with reproductive specialists for appropriate evaluation rather than relying on unproven dietary interventions 1, 7