Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/7/2025

Complications to Monitor in Patients with Achalasia

Primary Complications to Monitor

  • Patients with a history of achalasia should be primarily monitored for pulmonary aspiration, chest infections, persistent dysphagia, and weight loss as these are the most significant complications affecting morbidity and mortality 1
  • Pulmonary aspiration is a major complication due to food and fluid retention in the esophagus, which can lead to chest infections 1
  • Patients with achalasia are particularly prone to esophageal stasis, significantly increasing aspiration risk 1
  • Monitor for respiratory symptoms including cough, fever, and shortness of breath which may indicate aspiration pneumonia 1
  • Weight loss is a common complication due to reduced oral intake from dysphagia 1
  • Regular monitoring of weight and nutritional status is essential 1

Post-Treatment Complications

  • Risk of perforation is 0-7% (mostly 3-4%) with pneumatic dilatation procedures 1
  • Suspect perforation when patients develop pain, breathlessness, fever, or tachycardia 1
  • Perforation is more common during the first dilatation procedure and requires immediate medical attention 1
  • Gastroesophageal reflux commonly develops after successful treatment of achalasia 1
  • Usually mild and readily controlled with acid suppression but can lead to reflux esophagitis and stricture formation if untreated 1

Long-Term Monitoring Recommendations

  • Regular follow-up to assess symptom control and nutritional status 1
  • Patients should receive written information about warning signs requiring immediate medical attention 1
  • Chest x-ray and contrast study should be performed urgently if patients develop pain, breathlessness, fever, or tachycardia after procedures 1
  • Elderly patients have higher risk of complications from treatment procedures 1
  • Patients with comorbidities (ASA grades III-V) are at higher risk of cardiorespiratory events during procedures 1
  • Patients on anticoagulants require special management to reduce bleeding risk during procedures 1

Disease Evolution and Progression

  • The disease evolves over a variable timespan, potentially progressing from early symptoms to more severe manifestations 2