Naproxen Dosing and Administration Guidelines

Introduction to Naproxen Dosing

• The British National Formulary for Children (BNFC) recommends a dose of 5 to 7.5 mg/kg of naproxen every 12 hours for a 14-year-old girl, with dosing calculated based on weight 1

Safety Considerations and Monitoring

• Common adverse effects of naproxen include gastrointestinal discomfort, dyspepsia, and abdominal pain, and consider combining with a proton pump inhibitor or histamine H2 blocker if GI symptoms occur, and monitor for signs of GI bleeding, especially if there is a history of NSAID-associated upper GI tract bleeding, and avoid use in patients with severe hepatic impairment 2