Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/7/2025

Metronidazole Activity Against Parasites

Spectrum of Antiparasitic Activity

  • Giardia lamblia is highly effective with tinidazole as first-line and metronidazole as second-line treatment, as recommended by the Infectious Diseases Society of America 1

Clinical Implications

  • Topical metronidazole formulations are NOT effective for parasitic infections like trichomoniasis, with cure rates <50%, according to the Centers for Disease Control and Prevention 2