Management of Premature Adrenarche

Diagnostic Considerations

• True precocious puberty is excluded by the absence of breast development and suppressed gonadotropins, according to the Journal of Clinical Oncology guidelines 1

Management Plan

• Regular monitoring is recommended without specific treatment, with follow-up visits every 6-12 months to monitor growth velocity, bone age advancement, and pubertal development, as suggested by the Journal of Clinical Oncology 1
• If signs of true central puberty develop, such as breast development or accelerated growth velocity, further evaluation is recommended, as advised by the Journal of Clinical Oncology 1