Trazodone Dose Increase Considerations

Efficacy and Dosing

• The American Academy of Sleep Medicine does not recommend trazodone as a treatment for sleep onset or sleep maintenance insomnia, as evidence shows only minimal benefits at 50 mg doses 1, 2
• For patients with cardiovascular conditions, more careful monitoring is required during dose escalation, according to clinical guidelines 3

Alternative Treatment Options

• If the patient is seeking treatment primarily for insomnia, consider that trazodone is not recommended by guidelines for this purpose, and other medications like eszopiclone, zolpidem, or zaleplon for sleep onset issues, or suvorexant or doxepin for sleep maintenance issues may be considered 1, 2