Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 12/11/2025

Burning Mouth Syndrome Management

Introduction to BMS Treatment

  • The American Academy of Otolaryngology-Head and Neck Surgery recommends that systemic corticosteroids should not be used for burning mouth syndrome (BMS), as there is no evidence supporting their efficacy for this condition, and they carry substantial risks—particularly in older adults with pre-existing risk factors for osteoporosis, diabetes, and hypertension 1

Risks Associated with Steroid Use

  • Systemic corticosteroids cause sodium retention and can precipitate or worsen hypertension and heart failure, and induce insulin resistance, increasing risk of diabetes onset and progression, according to the American Academy of Otolaryngology-Head and Neck Surgery 1
  • The use of systemic corticosteroids increases the risk of cardiovascular disease, as stated by the American Academy of Otolaryngology-Head and Neck Surgery 1
  • Fracture risk increases within 3 months of starting corticosteroids, with greatest bone loss occurring early in treatment, as reported in the journal Gut 3
  • Systemic corticosteroids are associated with mood disorders, insomnia, psychosis, increased infection risk, peptic ulcers, cataracts, myopathy, and adrenal suppression with prolonged use, according to the American Academy of Otolaryngology-Head and Neck Surgery 1

Precautions for Steroid Use in Other Conditions

  • If systemic corticosteroids are considered necessary for a different oral condition in an elderly patient, precautions should include calcium and vitamin D supplementation, bisphosphonate therapy, proton pump inhibitor for gastrointestinal protection, and pneumocystis jirovecii prophylaxis, as recommended by Praxis Medical Insights 2, 3, 4

REFERENCES

1

clinical practice guideline: hoarseness (dysphonia) (update). [LINK]

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2018

3

Corticosteroid Use in Elderly Patients [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

4

Osteoporosis and PCP Prophylaxis in Myasthenia Gravis Patients on High-Dose Prednisone [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026