Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/16/2025

Treatment of Seborrheic Dermatitis in Children

First-Line and Second-Line Treatment Options

  • The American Academy of Dermatology recommends topical calcineurin inhibitors (TCIs) for facial and intertriginous areas where corticosteroids may cause adverse effects 1, 2
  • Tacrolimus 0.1% ointment is recommended for facial involvement by the American Academy of Dermatology 2, 3
  • Pimecrolimus 1% cream is another option for sensitive areas, as suggested by the American Academy of Dermatology 2
  • Low-potency topical corticosteroids can be used for short-term (less than 7 days) to control inflammation during flares, but should be used cautiously and for limited duration to avoid adverse effects, according to the American Academy of Dermatology and the Journal of Microbiology, Immunology and Infection 2, 4

Important Considerations

  • The American Academy of Dermatology advises avoiding long-term topical corticosteroids in children due to the risk of HPA axis suppression 2
  • Monitoring for irritation is necessary, as topical antifungals and calcineurin inhibitors may cause burning or stinging upon application, as noted by the American Academy of Dermatology 2