Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 11/6/2025

Trichomoniasis Infection and Complications

Clinical Manifestations and Complications

  • Trichomonas vaginalis is associated with pelvic inflammatory disease (PID) in some cases, though this represents local spread rather than systemic infection, according to the American Academy of Pediatrics 1
  • In men, Trichomonas vaginalis can cause urethritis, epididymitis, and prostatitis when symptomatic, but these remain localized infections, as reported by the American Academy of Pediatrics 1
  • Approximately 80% of men with Trichomonas vaginalis infection are asymptomatic, as noted by the American Academy of Pediatrics 1
  • Trichomoniasis is associated with premature rupture of membranes, preterm delivery, and low birthweight, as recommended by the Centers for Disease Control and Prevention (CDC) 2, 3
  • Trichomoniasis increases the risk of HIV transmission and acquisition, as reported by the American Academy of Pediatrics 1
  • Trichomoniasis may facilitate transmission of other sexually transmitted infections, according to the American Academy of Pediatrics 1

Clinical Guidelines and Recommendations

  • The CDC guidelines focus entirely on local symptoms and reproductive complications, with no mention of systemic septic presentations, as recommended by the CDC 2, 3, 4