Piperacillin/Tazobactam Dosing in Renal Impairment

Critical Safety Considerations

• Piperacillin accumulation in severe renal impairment increases the risk of CNS toxicity, particularly in patients with creatinine clearance less than 40 mL/min, according to the American Journal of Kidney Diseases 1, 2

Optimizing Therapeutic Outcomes

• No cited facts are available for this section.