Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 6/17/2025

Thyroid Nodules and Dysphagia

Introduction to Thyroid Nodules and Dysphagia

  • Dysphagia occurs in up to 56% of patients with certain thyroid conditions that affect surrounding structures, according to clinical practice guidelines from the American Academy of Otolaryngology-Head and Neck Surgery 1

Diagnostic Evaluation

  • High-resolution ultrasound is essential to characterize the nodule, including its size, location relative to the trachea and esophagus, and composition, as recommended by the American College of Radiology 2
  • Evaluation of vocal cord mobility is important to exclude other causes of dysphagia, as suggested by the National Comprehensive Cancer Network 3
  • Assessment for esophageal pathology is necessary to rule out other causes of dysphagia, as recommended by the American College of Radiology 4
  • Consideration of neuromuscular causes of dysphagia is important, as suggested by the European Society of Gastrointestinal Endoscopy, published in Gut 5

Additional Imaging and Treatment

  • If needed, CT or MRI may be considered to better visualize the relationship between the nodule and surrounding structures, especially if there's concern for substernal extension, as recommended by the American College of Radiology 2

REFERENCES

1

clinical practice guideline: improving voice outcomes after thyroid surgery. [LINK]

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2013

2

acr appropriateness criteria<sup>®</sup> thyroid disease. [LINK]

Journal of the American College of Radiology, 2019

3

medullary carcinoma. [LINK]

Journal of the National Comprehensive Cancer Network : JNCCN, 2010

4

acr appropriateness criteria<sup>®</sup> dysphagia. [LINK]

Journal of the American College of Radiology, 2019