Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 1/1/2026

Defibrillation Waveform Selection and Energy Settings

Waveform Types and Characteristics

  • Monophasic defibrillators deliver current in a single polarity; the two main subtypes are monophasic damped sinusoidal (MDS) and monophasic truncated exponential (MTE). 1
  • Biphasic defibrillators reverse current direction in two phases and are now incorporated in virtually all modern automated external defibrillators (AEDs) and manual defibrillators. 1, 2

Clinical Efficacy

First‑Shock Success and Energy Requirements

  • Monophasic shocks require higher energies and achieve lower first‑shock success compared with biphasic shocks. 1
  • Recommended initial energy for biphasic devices: 150–200 J for biphasic truncated‑exponential waveforms and 120 J for rectilinear biphasic waveforms (manufacturer‑specified). 3
  • Recommended initial energy for legacy monophasic devices: 360 J for the first and all subsequent shocks. 3

Subsequent Shock Strategy

  • For biphasic devices, the same or higher energy may be used for subsequent shocks; an optimal escalation algorithm has not been definitively established. 1, 2
  • For monophasic devices, continue delivering 360 J for each subsequent shock. 3
  • Human studies have found no evidence of harm from biphasic energies up to 360 J. 1, 2

Survival Outcomes

  • No specific waveform (biphasic or monophasic) has been consistently associated with higher rates of return of spontaneous circulation (ROSC) or survival to hospital discharge. 1, 2

Resuscitation Protocol Implications

  • The high first‑shock efficacy of biphasic defibrillators (>90 %) prompted adoption of a single‑shock strategy followed immediately by chest compressions, replacing the older three‑stacked‑shock sequence. 4, 3
  • After each shock, CPR should be resumed immediately without a pulse or rhythm check. 4, 3
  • The former three‑shock protocol caused 29–37 second interruptions in chest compressions, which are now avoided. 4, 3

Common Pitfalls

  • Shock success (termination of ventricular fibrillation) does not guarantee ROSC or survival; high‑quality CPR must continue regardless of waveform type. 1, 2

Defibrillator Effectiveness

Key Differences

  • The American Heart Association recommends biphasic defibrillators over monophasic defibrillators for treating ventricular fibrillation due to their higher first-shock success rates and lower energy requirements 5, 6
  • Biphasic waveforms demonstrate higher first-shock success rates (85-98%) for terminating ventricular fibrillation compared to monophasic waveforms 6, 7
  • Biphasic defibrillators can effectively terminate ventricular fibrillation at lower energy levels (typically 200 J or less) compared to monophasic defibrillators 6, 7

Clinical Recommendations

  • The American College of Cardiology recommends defibrillators using biphasic waveforms (BTE or RLB) for treatment of both atrial and ventricular arrhythmias (Class IIa, LOE B-R) 8, 7
  • No specific biphasic waveform has been proven superior to others for termination of ventricular fibrillation 6, 7

Practical Implications

  • For biphasic defibrillators, it is reasonable to use the manufacturer's recommended energy dose for the first shock 7
  • Biphasic defibrillators often adjust energy output based on patient impedance, which may improve efficacy 6, 7

REFERENCES