Adverse Reactions to Mirabegron

Common Adverse Effects

• The American College of Cardiology notes that hypertension occurs in 7.5-11.3% of patients taking mirabegron, compared to 7.6% of patients taking placebo 1
• Nasopharyngitis occurs in 3.5-3.9% of patients taking mirabegron, compared to 2.5% of patients taking placebo 1
• Urinary tract infections occur in 2.9-4.2% of patients taking mirabegron, compared to 1.8% of patients taking placebo 1
• Headache occurs in 2.1-3.2% of patients taking mirabegron, compared to 3.0% of patients taking placebo 1

Skin and Hypersensitivity Reactions

• The Journal of Allergy and Clinical Immunology reports that urticaria (hives) is a documented allergic-type reaction to mirabegron 2
• Leukocytoclastic vasculitis is a documented allergic-type reaction to mirabegron 2
• Rash and pruritus (itching) are documented allergic-type reactions to mirabegron 2
• Purpura is a documented allergic-type reaction to mirabegron 2
• Lip edema is a documented allergic-type reaction to mirabegron 2

Comparison to Other Drug Classes

• The Journal of Allergy and Clinical Immunology notes that mirabegron has a lower allergic reaction profile compared to certain antibiotics, such as carboplatin and fluoroquinolones 2
• The National Comprehensive Cancer Network notes that mirabegron has a lower allergic reaction profile compared to certain antibiotics, such as carboplatin 3