Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/30/2025

Aripiprazole Administration Considerations

Formulation Choices

  • When treating patients with schizophrenia who have difficulty swallowing, the formulation choice should be considered during initial prescription rather than modifying standard tablets, as recommended by the American Medical Association 1
  • For patients receiving aripiprazole for conditions like delirium in cancer patients, the medication is available in immediate-release formulations that may be more appropriate than attempting to crush standard tablets, according to the American Society of Clinical Oncology 2
  • When treating elderly patients, who may be more likely to have swallowing difficulties, special consideration should be given to using appropriate formulations rather than modifying tablets, as suggested by the American Geriatrics Society 3