Sotalol's Effect on Blood Pressure and Hypertension Management

Clinical Blood Pressure Effects

• The American College of Cardiology/American Heart Association explicitly lists "decreased blood pressure" as a documented side effect, with a discontinuation rate of 5.9% in sotalol-treated patients versus 2.9% in controls 1
• Sotalol can be therapeutically beneficial in hypertensive patients with atrial fibrillation, simultaneously addressing both rhythm control and blood pressure management 1

Contraindications and Precautions

• The drug should not be used in patients with heart failure or left ventricular dysfunction unless an ICD has been implanted, based on the d-sotalol mortality data 2
• Sotalol is contraindicated in asthma, heart failure, renal insufficiency, or QT prolongation 3