Medications for Hyperthyroidism in Patients Taking Losartan
Special Considerations with Losartan
- Losartan can be safely continued in patients requiring treatment for hyperthyroidism as there are no significant contraindications to combining it with antithyroid medications, according to the European Society of Cardiology and the American Heart Association 1, 2
- Losartan has demonstrated cardiovascular benefits in hypertensive patients, including those with diabetes and left ventricular hypertrophy, making it a suitable ongoing therapy while treating hyperthyroidism, as recommended by the European Society of Cardiology and the American Stroke Association 3, 1
Treatment Algorithm for Hyperthyroidism in Patients on Losartan
- Continue standard dosing of losartan for blood pressure management, as recommended by the European Society of Cardiology 1, 2
- Monitor blood pressure closely as thyroid function normalizes, as dosage adjustments may be needed, according to the European Society of Cardiology 1
- Consider the cardioprotective benefits of losartan, especially in patients with left ventricular hypertrophy, as suggested by the American Stroke Association and the European Society of Cardiology 3, 1
Surgical Considerations
- Losartan can be safely continued perioperatively with appropriate blood pressure monitoring, as recommended by the American Stroke Association 3
Monitoring and Follow-up
- Assess blood pressure regularly as thyroid function normalizes, as requirements for antihypertensive therapy may change, according to the European Society of Cardiology and the American Heart Association 1, 2
Potential Pitfalls and Caveats
- Normalizing thyroid function may alter blood pressure control, requiring adjustment of losartan dosage, as recommended by the European Society of Cardiology 1