Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 11/28/2025

Vaccination and Screening Guidelines for Adults

Core Vaccinations

  • The American College of Physicians recommends administering influenza vaccine annually using standard-dose quadrivalent inactivated vaccine to all adults, including those with no significant medical history 3, 1
  • The Centers for Disease Control and Prevention recommends giving one dose of Tdap if not previously received in adulthood, then Td booster every 10 years 4, 1
  • The American Academy of Family Physicians recommends administering 3-dose series of HPV vaccine (Gardasil 9) at 0, 1-2, and 6 months for men through age 26; may consider for ages 27-45 if likely to have new sexual partners 4, 5, 1
  • The American Association for the Study of Liver Diseases recommends universal vaccination for all adults aged 19-59 years with hepatitis B; use HEPLISAV-B (2-dose series at 0 and 1 month) or traditional 3-dose series (0, 1, and 6 months) 5, 1

Essential Laboratory Tests

  • The American Diabetes Association recommends diabetes screening using HbA1c, fasting plasma glucose, or 2-hour OGTT; repeat every 3 years if normal 2
  • The American Heart Association recommends fasting lipid profile including total cholesterol, LDL, HDL, and triglycerides to assess cardiovascular risk 2
  • The National Kidney Foundation recommends comprehensive metabolic panel including electrolytes, creatinine with eGFR, liver function tests (ALT, AST, total bilirubin, alkaline phosphatase) 2
  • The American College of Physicians recommends complete blood count (CBC) to provide baseline hematologic assessment 2

Important Clinical Considerations

  • The Centers for Disease Control and Prevention recommends administering vaccines regardless of timing of other healthcare visits; do not delay vaccination until "complete" preventive visit 1
  • The American Academy of Family Physicians recommends that multiple vaccines can be given during the same visit at different anatomic sites 3, 4
  • The American Heart Association recommends against ordering non-fasting lipid panels when fasting values are required for accurate cardiovascular risk assessment 2
  • The American Diabetes Association recommends against using point-of-care HbA1c devices for diagnosis without quality assurance; only laboratory-based NGSP-certified methods should be used 2
  • The American College of Physicians recommends against failing to assess family history, as this significantly impacts screening recommendations for diabetes, cardiovascular disease, and cancer 2
  • The American Association for the Study of Liver Diseases recommends against assuming immunity to hepatitis B without documentation; many adults lack adequate vaccination records 5, 1