H. pylori Infection and Gastritis

Clinical Significance and Management

• H. pylori gastritis can progress to severe gastroduodenal pathologies, including gastric cancer 1
• Eradication of H. pylori heals gastritis 2
• Eradication of H. pylori prevents progression to atrophic gastritis in patients receiving long-term PPI therapy 3
• Eradication of H. pylori is recommended for prevention of gastric cancer, especially before the development of preneoplastic conditions 1
• Long-term PPI treatment in H. pylori-positive patients can accelerate progression to atrophic gastritis 3