Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/3/2025

Management of Brain Contusion

Immediate Pre-Hospital and Emergency Stabilization

  • The American College of Surgeons recommends establishing airway control as the absolute priority with tracheal intubation and mechanical ventilation for severe TBI patients, beginning in the pre-hospital period 3
  • Monitoring end-tidal CO2 continuously is crucial to maintain PaCO2 within normal range, as hypocapnia induces cerebral vasoconstriction and risks brain ischemia 3
  • Confirming correct tracheal tube placement through EtCO2 monitoring is essential 3
  • Maintaining systolic blood pressure >110 mmHg from first contact is critical, as even a single episode of hypotension (SBP <90 mmHg) markedly worsens neurological outcome 1
  • Using vasopressors (phenylephrine or norepinephrine) immediately for hypotension rather than waiting for fluid resuscitation or sedation adjustment is recommended, as these have delayed hemodynamic effects 1

Imaging Strategy

  • Obtaining non-contrast brain and cervical spine CT immediately without delay is necessary to guide neurosurgical procedures and monitoring techniques 1, 2
  • Using inframillimetric sections reconstructed with thickness >1mm, visualized with double fenestration (central nervous system and bone windows) is recommended 1

Neurosurgical Intervention Criteria

  • Performing surgical evacuation for symptomatic extradural hematoma, acute subdural hematoma with thickness >5mm and midline shift >5mm, brain contusions with mass effect, acute hydrocephalus requiring drainage, open displaced skull fracture, and closed displaced skull fracture with brain compression is recommended 1, 2, 3

Intracranial Pressure Management

  • Implementing ICP monitoring in severe TBI to detect intracranial hypertension and guide ICP-directed therapy is essential 1, 2, 3
  • Maintaining normothermia using targeted temperature control is crucial, as hyperthermia increases complications and unfavorable outcomes including death 1, 2

Supportive Care Measures

  • Implementing detection and prevention strategies for post-traumatic seizures is recommended 2
  • Maintaining biological homeostasis including osmolarity, glycemia, and adrenal axis function is necessary 2

Critical Pitfalls to Avoid

  • Never allowing even brief episodes of hypotension while waiting for "adequate resuscitation" before starting vasopressors is critical 1
  • Never using bolus sedation rather than continuous infusions, which causes hemodynamic instability 1
  • Never delaying transfer to specialized neurosurgical center for "stabilization" at non-neurosurgical facility 1

REFERENCES

2

Management of Contrecoup Cerebral Injury [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

3

Traumatic Brain Injury Management [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025