Evidence-Based Drug Treatments for Capsular Contracture in Breast Augmentation

Risk Factors for Capsular Contracture

• Previous radiotherapy to the breast increases the risk of developing capsular contracture, as reported by the American Society of Clinical Oncology 1

Clinical Implications

• The National Comprehensive Cancer Network recommends that patients should be counseled about the increased risk of capsular contracture when post-mastectomy radiation is required, with an increased rate of capsular contracture associated with immediate implant reconstruction 2 3
• The American College of Radiology notes that tissue expansion of irradiated skin can result in significantly increased risk of capsular contracture, and an implant that becomes more rounded in appearance may signify the presence of capsular contracture 2 3 4