Cefepime-Induced Liver Injury

Introduction to Hepatotoxicity

• The American Academy of Child and Adolescent Psychiatry notes that patients with schizophrenia or bipolar disorder on psychotropic medications may already have baseline transaminase elevations, complicating the clinical picture when cefepime is administered 1

High-Risk Populations and Clinical Considerations

• Patients with psychiatric conditions, such as schizophrenia or bipolar disorder, who are on psychotropic medications, may have elevated transaminases, requiring special attention when cefepime is prescribed, according to the Journal of the American Academy of Child and Adolescent Psychiatry 1