Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/18/2025

Management of Asthma with Concurrent Allergic Rhinitis

Introduction to Asthma Management

  • The American Academy of Otolaryngology-Head and Neck Surgery recommends adding a leukotriene receptor antagonist (LTRA) for patients with poorly controlled asthma and concurrent allergic rhinitis despite high-dose inhaled corticosteroids (ICS) plus long-acting beta-agonist (LABA) 1, 2

Rationale for LTRA as Add-On Therapy

  • The American Academy of Otolaryngology-Head and Neck Surgery suggests that LTRAs are specifically recommended for patients with concurrent asthma and allergic rhinitis, providing a dual benefit for both conditions 1, 3
  • The American Journal of Respiratory and Critical Care Medicine indicates that Step 4 therapy, which includes the addition of an LTRA, is warranted for patients with persistent symptoms post-exacerbation despite high-dose ICS plus LABA 4
  • Rhinology guidelines state that the combination of ICS with LTRA provides significantly greater efficacy in reducing airflow obstruction compared to doubling the ICS dose 5

Additional Management Considerations

  • The American Academy of Otolaryngology-Head and Neck Surgery recommends optimizing intranasal corticosteroids, as treatment of allergic rhinitis reduces bronchial hyperreactivity and improves asthma control 3
  • The American Journal of Respiratory and Critical Care Medicine suggests verifying adherence and technique, including checking inhaler technique and assessing medication adherence 7
  • The American Family Physician guidelines recommend reviewing the patient's action plan and ensuring they understand when to escalate therapy 8

Expected Timeline and Follow-Up

  • The American Family Physician suggests reassessing the patient in 2-4 weeks to evaluate response to LTRA addition, checking symptom scores, peak flow measurements, and rescue medication use 8
  • The American Academy of Otolaryngology-Head and Neck Surgery recommends considering immunotherapy if combination pharmacotherapy fails to achieve control, as it can benefit both asthma and rhinitis 1, 3

REFERENCES

1

clinical practice guideline: allergic rhinitis. [LINK]

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2015

2

Management of Allergic Asthma and Rhinitis in Patients with Selective IgA Deficiency [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

3

clinical practice guideline: allergic rhinitis. [LINK]

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2015

4

optimal asthma control: time for a new target. [LINK]

American Journal of Respiratory and Critical Care Medicine, 2020