Physical Examination Findings of Molluscum Contagiosum

Key Physical Examination Findings

• The American Academy of Pediatrics notes that Molluscum contagiosum presents as skin-colored papules that develop a characteristic central umbilication as they age, typically affecting the trunk, face, and extremities in children 1, 2
• Skin-colored, whitish, or pink papules with a shiny surface and central umbilication are common, and most commonly affect the trunk, face, and extremities in children 1, 3

Distribution Patterns

• In children, the condition commonly affects the trunk, face, and extremities 1
• In immunocompromised patients, Molluscum contagiosum can be more extensive with atypical presentations 3

Associated Findings

• The condition is mostly asymptomatic but may present with pain, itching, redness, and occasional bacterial superinfection 1

Atypical Presentations

• In immunocompromised patients, especially those with HIV, multiple large lesions may resemble other conditions 5
• Umbilicated papules resembling Molluscum contagiosum can be seen in cryptococcal infections in HIV patients 6

Clinical Course

• Lesions typically persist for 6-12 months but can last up to 4 years 1
• In immunocompromised patients, lesions may persist longer and be more extensive 3

Diagnostic Clues

• When examining eyelid lesions, look for associated conjunctivitis which may be mild to severe with follicular reaction 3
• Eyelid involvement may cause associated conjunctivitis 3, 4