Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/25/2025

Treatment for Stye (Hordeolum)

First-Line Treatment

  • The American Academy of Ophthalmology recommends applying warm compresses to the affected eyelid for several minutes (typically 5-10 minutes) to soften adherent debris and warm the meibomian secretions 1, 2
  • Warm compresses should be performed once or twice daily at times convenient for the patient 2
  • Gentle eyelid cleansing and massage should be done after warm compresses to help express the contents of the affected gland 1, 2
  • Eyelid cleansing can be accomplished by gently rubbing the base of the eyelashes using either diluted baby shampoo or commercially available eyelid cleaner on a cotton ball, cotton swab, or clean fingertip 2
  • Eye cleaners with hypochlorous acid at 0.01% have a strong antimicrobial effect and can be used for treatment 2

Important Technique Considerations

  • When applying warm compresses, use water that is warm but not hot enough to burn the skin 1
  • For sustained warmth, options include hot tap water on a clean washcloth, over-the-counter heat packs, or homemade bean/rice bags that can be heated in the microwave 1
  • Patients with neurotrophic corneas need proper counseling to avoid injury to corneal epithelium during eyelid cleansing 2
  • Patients with advanced glaucoma should be advised not to apply excessive pressure on the eyelids as it may increase eye pressure 2

Second-Line Treatment

  • A topical antibiotic ointment such as bacitracin or erythromycin can be prescribed and applied to the eyelid margins one or more times daily or at bedtime for a few weeks 2
  • The frequency and duration of antibiotic treatment should be guided by the severity of the condition and response to treatment 2
  • Topical antibiotics have been shown to provide symptomatic relief and decrease bacteria from the eyelid margin 2

For Severe or Recurrent Cases

  • For moderate to severe cases, especially prior to intraocular surgery, topical antibiotics combined with eyelid hygiene are recommended 1
  • Patients should be advised that warm compress and eyelid cleansing treatment may be required long-term, as symptoms often recur when treatment is discontinued 2

Treatment Duration and Follow-up

  • Follow-up should be based on the severity of the condition and response to treatment 2

Cautions

  • Cleaning the eyelid can be dangerous if the patient lacks manual dexterity or the necessary skill to perform the task safely 2
  • Long-term antibiotic treatment may result in the development of resistant organisms 1
  • If a stye is markedly asymmetric, resistant to therapy, or recurrent in the same location, consider biopsy to exclude the possibility of carcinoma 3