Antipyretic Therapy in Patients on Eliquis

Safety and Efficacy Considerations

• Acetaminophen is generally well-tolerated and has a better safety profile compared to NSAIDs in terms of gastrointestinal and cardiovascular effects 1
• The European Heart Journal recommends acetaminophen as a non-sedating adjunct for managing conditions like shivering due to its favorable safety profile 2, 3
• Be cautious with acetaminophen in patients with chronic alcohol use or liver disease, as toxicity can occur at lower doses in these populations 4