Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 7/18/2025

Sexually Transmitted Infections in the United States

Epidemiology

  • The southeastern United States consistently reports the highest rates of sexually transmitted infections (STIs) and sexually transmitted diseases (STDs) in the country, with a geographic overlap between regions with high STD rates and rapidly expanding heterosexual HIV transmission 1
  • The southeastern United States shows disproportionately high rates of notifiable STDs, particularly gonorrhea and syphilis 1
  • This regional concentration reflects a concerning pattern where STD rates and heterosexual HIV transmission overlap geographically 1
  • Chlamydia remains the most commonly reported infectious disease in the United States 1
  • African Americans experience approximately fiftyfold higher rates of primary and secondary syphilis compared to whites 1
  • Sexually active adolescents across the United States have a point prevalence for chlamydial infection of 5-10% 1
  • In 1996, routine reporting indicated a gonorrhea case rate of 3% for African-American women aged 15-19 years and men aged 20-24 years 1

HIV Transmission and Acquisition

  • The southeastern United States is experiencing an increasing proportion of AIDS cases, particularly among young women 1
  • The shift in the HIV/AIDS epidemic toward African Americans reflects and may be partly attributable to the long-standing disproportionate burden of other STDs in this group 1

Access to Care

  • Only about half of local public health departments in the United States provide STD preventive services 1
  • Access to care is often restricted by limited hours of operation and lack of timely services 1
  • Nearly 40% of local health departments providing STD services cannot see potentially infected patients the same day they seek care 1
  • In primary care settings, most providers do not routinely obtain sexual histories or screen for STDs 1