Treatment of Allergic Rhinitis in Children with Fluticasone Furoate

Dosing Guidelines

• The American Academy of Otolaryngology-Head and Neck Surgery recommends a dose of 2 sprays per nostril once daily (total daily dose of 110 μg) for children over 8 years old with allergic rhinitis 1, 2
• For children aged 2-11 years, the recommended starting dose is 1-2 sprays per nostril once daily 1, 2
• The dose may be reduced to the minimum effective dose for maintenance therapy once symptoms are controlled 3

Efficacy and Safety Considerations

• Intranasal corticosteroids, such as fluticasone furoate, are the most effective medications for treating allergic rhinitis, with an onset of therapeutic effect between 3-12 hours after administration 3
• The optimal efficacy of fluticasone furoate is reached within days to weeks, with a good safety profile in children and no significant effect on growth at recommended doses 3, 4

Safety Profile in Children

• Fluticasone furoate has a good safety profile in children, with common side effects including epistaxis, headache, pharyngolaryngeal pain, nasal ulceration, back pain, pyrexia, and cough 1, 2
• The medication is contraindicated in children with a history of hypersensitivity to fluticasone furoate or any components of the formulation 1

Administration Technique and Treatment Considerations

• Regular use of fluticasone furoate rather than an as-needed approach is recommended for optimal symptom control, with proper administration technique demonstrated to ensure effective delivery and minimize side effects 3, 4
• The child should be instructed to shake the bottle prior to use, blow their nose before using the spray, and keep their head in an upright position during administration 4