Symbicort Dosing for COPD Management
Recommended Dosing Regimen and Patient Selection
- For patients with severe COPD and a history of repeated exacerbations, the American Thoracic Society recommends Symbicort (budesonide/formoterol) at a dose of 160 μg/4.5 μg, two inhalations twice daily, with a total daily dose of 320/9 μg per inhalation and 640/18 μg total daily 1, 2
Clinical Outcomes with Recommended Dosing
- The Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines support the use of Symbicort in patients with severe and very severe disease experiencing repeated COPD exacerbations, where an inhaled corticosteroid should be added to long-acting bronchodilators, resulting in improved symptom scores and health status beyond monotherapy 1, 2