Mechanism of Memantine in Neuroprotection

Clinical Efficacy and Neuroprotection

• The American College of Physicians, as reported in the Annals of Internal Medicine, suggests that memantine prevents excess stimulation of the glutamate system, which influences memory and learning 1, 2, 3
• The use of memantine as an adjunct to whole-brain radiation therapy shows a trend toward preservation of delayed recall and significantly longer time to cognitive decline, according to Neuro-Oncology 4