Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/28/2025

Risk Factors for Vasa Previa

Primary Risk Factors

  • Velamentous cord insertion, where the umbilical cord inserts into the membranes rather than directly into the placenta, creating unprotected fetal vessels that can traverse the cervix, is a significant risk factor, as noted by the American College of Radiology 1, 2
  • Multiple gestations, such as twin pregnancies, have a higher frequency of velamentous cord insertion and consequently vasa previa, according to the American College of Radiology 1, 2, 3

Additional Risk Factors

  • Prior uterine surgery, including cesarean delivery and other procedures that may affect placentation, is a risk factor, as reported by the American College of Radiology 4, 5

Screening Recommendations

  • Evaluation of placental cord insertion site during the 20-week anatomy scan can help identify cases at risk, and special attention should be paid to the placenta, umbilical cords, and cervix during anatomical survey of multiple gestations, as recommended by the American College of Radiology 1, 3

Diagnostic Pitfalls to Avoid

  • Digital pelvic examination without first excluding vasa previa can trigger vessel rupture, as warned by medical guidelines 7

REFERENCES

1

acr appropriateness criteria<sup>®</sup> multiple gestations. [LINK]

Journal of the American College of Radiology, 2017

2

acr appropriateness criteria<sup>®</sup> multiple gestations. [LINK]

Journal of the American College of Radiology, 2017

3

acr appropriateness criteria<sup>®</sup> multiple gestations. [LINK]

Journal of the American College of Radiology, 2017

4

acr appropriateness criteria® placenta accreta spectrum disorder. [LINK]

Journal of the American College of Radiology, 2020

5

acr appropriateness criteria® placenta accreta spectrum disorder. [LINK]

Journal of the American College of Radiology, 2020

6

Management and Treatment of Placenta Previa [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025