Pre-Conception Planning for Ozempic Discontinuation

Clinical Guidelines

• The American Gastroenterological Association recommends that medications like ozanimod be stopped at least 6 months before conception, and semaglutide is considered a medication that requires discontinuation before pregnancy planning 1
• Women taking medications with potential teratogenic effects, such as Ozempic, should discuss family planning with their healthcare provider well in advance, according to clinical guidelines from the American College of Gastroenterology 2

Comparison to Other Medications

• Methotrexate is recommended to be discontinued 3 months before conception, as suggested by the American College of Rheumatology 3
• Cyclophosphamide is recommended to be discontinued 3 months before conception, as recommended by the European League Against Rheumatism 4

Management During the Transition Period

• Alternative treatments for the underlying condition, such as diabetes or weight management, that are pregnancy-compatible should be considered, as suggested by the American Diabetes Association 2