Albumin Administration and Diuretic Management in Cirrhotic Third‑Space Edema
1. Albumin Dosing Recommendations
2. Timing of Diuretic Restart After Albumin
3. Monitoring During the 72‑Hour Observation Period
| Parameter | Expected Findings | Action Threshold |
|---|---|---|
| Body weight | Loss of ~0.5–1 kg/day if diuresis is adequate | Persistent weight gain suggests inadequate fluid mobilization |
| Serum creatinine | Stable or decreasing; rise >0.3 mg/dL indicates volume depletion/AKI | Do not restart diuretics; evaluate for hepatorenal syndrome |
| Serum sodium | Remains ≥125 mmol/L; drop below 125 mmol/L warrants fluid restriction | Do not restart diuretics |
| Clinical exam | Resolution of peripheral edema and ascites | Guides decision to resume or withhold diuretics |