Duration of Clotiazepam Effect

Comparison with Other Benzodiazepines

• The American Academy of Pediatrics notes that diazepam has a duration of action of 15-21 hours in children aged 2-12 years, and 18-20 hours in adolescents aged 12-16 years 1, 2
• The lorazepam has a duration of action of approximately 10.5 hours (range 6-17 hours) in children 1, 2
• The clonazepam has a duration of action of 22-33 hours 1, 2

Special Considerations

• The Pediatrics society reports that flunitrazepam (Rohypnol) can have effects lasting up to 8-12 hours (or up to 36 hours when combined with alcohol), whereas clotiazepam has a shorter duration 3