Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 2/2/2026

Safety Profile of Loratadine in Pediatric Patients

Non‑Sedating Antihistamine

  • Loratadine is a second‑generation antihistamine that does not cause sedation at the recommended pediatric dose, distinguishing it from first‑generation antihistamines (e.g., diphenhydramine) and supporting its use in children. [1][2]

REFERENCES

2

clinical practice guideline: allergic rhinitis. [LINK]

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2015